Asthma/COPD Flare

Initial pharmacologic therapy

Beta adrenergic agonists

Ipratropium

also available in an MDI that can be used with a spacer, 2 to 4 inhalations every hour for two to three doses, and then every two to four hours as needed.

Systemic glucocorticoids

Antimicrobial therapy

Recommend antibiotics with at least two of these three symptoms – increased dyspnea, increased sputum volume, or increased sputum purulence.

Oxygen therapy

Supplemental oxygen be titrated to a target of 88 to 92 percent pulse oxygen saturation, rather than using high-flow, nontitrated oxygen

https://www.uptodate.com/contents/copd-exacerbations-management/abstract/1,17,

https://www.uptodate.com/contents/copd-exacerbations-management/abstract/33

https://www.uptodate.com/contents/copd-exacerbations-management/abstract/12,34,35

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Revision #2
Created 25 February 2022 06:39:12 by Katarina Soewono
Updated 3 April 2022 09:08:42 by Katarina Soewono