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Medication in Obstetrics

Minimize all medication use during pregnancy (especially in 1st TM), unless clearly indicated!

FDA pregnancy categories

A: No risk in controlled human studies

B: No risk in controlled animal studies and no risk seen in humans

C: Small risk in controlled animal studies, but not seen or not studied in humans

D: Strong evidence of risk in humans but benefit may outweigh tisk

X: High risk - never to be used in pregnant humans

Analgesics

  • Acetaminophen - B / compatible with breastfeeding
  • Ibuprofen - C 1st/2ndTM ; D 3rdTM / compatible with breastfeeding
  • Fentanyl - C / compatible with breast feeding
  • Hydromorphone (Dilaudid) - C / compatible with breast feeding
  • Morphine - C / Compatible with breast feeding
  • Oxycodone (Percoset) - B / Compatible with breast feeding
  • Hydrococone (Vicodin) - C / Compatible with breast feeding

Antibiotics

  • Ampicillin - B / Compatible with breast feeding
  • Amoxicillin - B / Compatible with breast feeding
  • Cefazolin - B / Compatible with breast feeding
  • Gentamicin - D / Compatible with breast feeding
  • Clindamycin - B / Avoid if possible in breast feeding, monitor infant
  • Cipro - C (avoid in pregnancy) / Avoid if possible in breast feeing, monitor infant
  • TMP-SMX - D / infant risk minimal in breast feeding
  • Nitrofurantoin - B / Compatible with breast feeding
  • Ceftriaxone - B / Compatible with breast feeding
  • Zosyn - B / Compatible with breast feeding
  • Erythromycin - B / infant risk minimal in breast feeding
  • Vanco - C / infant risk cannot be ruled out in breast feeding
  • Keflex - B / Compatible with breast feeding
  • Flagyl - B / Infant risk cannot be ruled out, avoid if possible in breast feeding
  • Doxycycline - D / avoid in breast feeding

Anticoagulation

  • Lovenox - B / Compatible with breast feeding

 

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